DiaLine Excellence

AVE 333 Dry Chemical Analyzer for Vaginal Secretions

REFERENCE ID: I6436H5384

This Fully Automated Integrated Vaginal Microecology Analyzer is a high-throughput clinical workstation combining 11-parameter dry chemistry and AI-driven morphological microscopy for comprehensive vaginal health profiling.

Brand AVE

Availability By Request

Detailed Information

Product Overview

This Fully Automated Integrated Vaginal Microecology Analyzer is an advanced, high-throughput diagnostic workstation designed for comprehensive vaginal discharge profiling. Combining non-contact dry chemistry (up to 11 parameters) and automated AI-driven morphological microscopy, it automatically identifies, classifies, and quantifies both chemical biomarkers and pathological formed elements (including Trichomonas, clue cells, fungi, and bacterial morphotypes) to provide automated Nugent and Donders scoring from a single sample run.

Highlights & Key Advantages

2-in-1 Integrated Morphological & Chemical Detection: Combines physical, chemical, and microscopic formed elements analysis in a single sample run, eliminating diagnostic blind spots, improving laboratory efficiency, and reducing manual labor.
Automated Microscopic Image Acquisition: Employs AI and machine vision to automate microscopic examinations, utilizing low-magnification for rapid full-field positioning and high-magnification for precise target tracking and high-resolution imaging.
AI-Powered Morphological Recognition: Utilizes deep learning and autonomous learning algorithms trained on a massive database to recognize, classify, and count RBCs, WBCs, epithelial cells, clue cells, Trichomonas, and bacterial morphotypes with over 95% accuracy.
Precise Temperature-Controlled Incubation: Features an integrated 37°C constant temperature incubation system with 100 incubation positions to maintain optimal reaction environments.
High-Throughput Sedimentation: Utilizes high-precision disposable counting plates, supporting up to 6 plates simultaneously (time-sharing sedimentation) to achieve a throughput of ≥ 120 tests per hour.
Worry-Free Biosafety: Implements a fully sealed specimen collection system, closed-cap puncture sampling (preventing aerosol exposure), and contact-free specimen handling.
Real-Scene Traceability: Delivers real-time microscopic images and dynamic videos of motile pathogens (such as Trichomonas vaginalis) for complete clinical validation and case traceability.
Worry-Free After-Sales: Offers a simple and convenient QR-based service request feature, allowing users to instantly report issues and minimize downtime.

Testing Parameters Detected

• Morphological Detection Items:
Red Blood Cells, White Blood Cells, Epithelial Cells, Clue Cells, Vaginal Trichomonas, Cocci, Bacilli, Fungi, Pathogenic Microorganisms.

• Additional Indicators (Expandable):
Bacterial Density, Diversity, Dominant Bacteria, Nugent Score, Donders Score.

• Dry Chemical Detection Items (11 Parameters):
• pH: An important indicator reflecting the vaginal microecological balance.
• Hydrogen Peroxide (H₂O₂): A metabolite of lactobacilli; its concentration correlates positively with their quantity, indicating normal function.
• Lactic Acid (LA): Evaluates lactobacillus levels to check vaginal flora balance.

• Leukocyte Esterase (LE): An inflammatory marker, reflecting the quantity of white blood cells in vaginal secretions.
• Sialidase (SNA): Secreted by Gardnerella and other anaerobes; a positive result suggests bacterial vaginosis (BV).
• Beta-Glucuronidase (β-G): An enzyme secreted by aerobic bacteria; positive suggests aerobic bacterial vaginitis (AV).
• N-Acetylglucosaminidase (NAG): Secreted by fungi and trichomonads; combined with pH, indicates fungal vaginitis (pH ≤ 4.6) or trichomoniasis (pH > 4.8).
• Proline Aminopeptidase (PLD): Positive suggests fungal vaginitis or anaerobic bacterial infections.
• Coagulase (CG): Enzyme secreted by aerobic bacteria; positive indicates aerobic bacterial vaginitis.
• Oxidase (OX): Positive suggests gonococcal infection.
• Alkaline Phosphatase (ALP): Positive suggests mixed vaginitis.

Technical Work Principles

Morphological Detection: Utilizes artificial intelligence (AI) and machine vision technology to capture high-resolution images, classify, and count microscopic elements automatically.
Dry Chemical Detection (Colorimetric Analysis): Based on the Beer-Lambert Law, optical photodiode systems measure color intensity changes on dry reagent strips to quantify analyte concentrations.

Performance Specifications

Testing Criteria	Performance Evaluation
Throughput	≥120 tests/h
Detection Rate	>90% for samples at concentration of 5 cells/μL
Accuracy	Microscopy: >95% \| Chemistry: Within 1 tolerance level (no false positives/negatives)
Repeatability	Microscopy: CV<25% (at 50 cells/μL), CV<15% (at 200 cells/μL) \| Chemistry: CV<1%
Carryover	Microscopy: <1 cell/μL (at 5000 cells/μL) \| Chemistry: No false positives
Report Output	Comprehensive reports integrating images and diagrams, showing microscopy, morphological analysis, and chemical results
Sampler Capacity	Loading capacity of 60 samples in racks (STAT available)
Result Storage	≥1,000,000 results
Connectivity	Bidirectional data transmission with LIS/HIS (network function)

Working Procedure

Refer to the standard automated laboratory workflow diagram below for sample handling, incubation, and microscopic imaging steps:

Figure: Standard Automated Working Procedure

Recommended For

Hospitals, High-Volume Clinical Laboratories, Private Laboratories, Gynecology & Obstetrics Clinics, Diagnostic Centers

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